In the game, players work together to defeat one of two villains: Mothman or the Martian Invader. Each villain has a unique battlefield with unique objectives. If the villain completes their objective (or defeats the heroes), the players lose. The villains are aided by a number of possible minions: Jersey Devil, Ant Queen, Loveland Frog, The Blob, Tarantula, and Skunk Ape. The enemies use special action cards and a simple targeting scheme to control their movement and attacks. The set comes with four new heroes: Nikola Tesla discharges his electrified coils to power up his effects; Annie Christmas gets stronger when she's fighting from behind; The Golden Bat, the world's first superhero, has a variety of powerful effects; and Dr. Jill Trent, Science Sleuth, calls on a collection of gizmos.